Publications by Dr. Paul Clayton


For good health it is vitally important to maintain the right balance of anti- and pro-inflammatory elements in the diet, and in the body. Taking the recommended daily doses of Active oil and Protect provides an optimal combination of 1-3, 1-6 beta glucans, polyphenols, Omega-3’s and co-factors. This combination offers extensive protection against infectious, allergic and degenerative health issues.

There are two fundamentally different kinds of inflammation. The acute inflammatory response is generally positive; it is a critically important part of the body’s defence against invading pathogens, and the response to injury. But if acute inflammation fails to resolve the immediate problem, or if the body is frequently exposed to dietary and other toxins, chronic inflammation may develop. And this is overwhelmingly negative. Chronic inflammation is now known to play a critical role in driving most and perhaps all the chronic degenerative health issues.

There is overwhelming evidence that we have become, over the last century, far more prone to chronic inflammation and the health issues that it creates. This is due to increased levels of pro-inflammatory elements in our diet and environment; and the progressive removal of anti-inflammatory compounds from our diet. Key anti-inflammatory nutrients include the yeast-derived 1-3, 1-6 beta glucans, the polyphenols, and the omega-3 polyunsaturated fatty acids. The resulting increase in chronic inflammation explains exactly why degenerative health issues, the so-called 'diseases of civilisation', have become so much more prevalent.

Yeast-derived 1-3, 1-6 beta glucans increase the effectiveness of acute inflammation, improving the body’s ability to deal with pathogens quickly and effectively and thus reducing the likelihood of damaging chronic inflammatory reactions. Vital co-factors like iodine, vitamins A and D, and the minerals selenium, zinc and iron, are all needed for optimal immune function. These yeast derivates also exert direct anti-inflammatory effects in the gut, via dectin receptors.

Polyphenols, compounds found in plant foods such as olives, are powerful anti-inflammatory agents which block inflammatory and tissue-destructive enzymes. Polyphenols also possess antioxidant properties which protect the body from oxidative stress. 


Omega-3 and Omega-6 fatty acids in the diet are built into the membranes of our cells. Omega-6's generate pro-inflammatory metabolites such as IL-1 beta, IL-2, IL-6 and TNF-alpha, while Omega-3's form anti-inflammatory metabolites. Consequently, an Omega-6/Omega-3 ratio of 9:1 or higher worsens symptoms in inflammatory conditions, while a ratio lower than 5:1 has a beneficial effect. A ratio below 3:1 suppresses inflammation.